Antibody-Drug Conjugates
Internalized Drug-Antibody Complex

Internalized Drug-Antibody Complex

Final published figure

Final published figure

Antibody (Heavy chain gray, light chain black) conjugated to the chemotherapeutic drug (yellow)

Antibody (Heavy chain gray, light chain black) conjugated to the chemotherapeutic drug (yellow)

Bound antibody

Bound antibody

Degraded antibody releasing the drug

Degraded antibody releasing the drug

Initial layout mockup

Initial layout mockup

Antibody-Drug Conjugates

Artwork for Figure 1 in the review article "Antibody-drug conjugates: a clinical pharmacy perspective on an emerging cancer therapy" published in the journal Pharmacotherapy, 36(1): 99-116, by Jerjian TV, Glode AE, Thompson LA, and O’Bryant CL. Cancer drugs can be conjugated to antibodies that recognize specific proteins on the surface of cancer cells. This allows a much more targeted approach to specifically kill cancer cells while reducing the toxicity associated with traditional chemotherapy. When it works anyway...

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